在最新一期(6月20日)的《细胞》（Cell）杂志上，复旦大学的研究人员以“Riboswitch Regulation of Aminoglycoside Resistance Acetyl and Adenyl Transferases”为题，就耶鲁大学的Adam Roth博士和Ronald R. Breaker教授针对该研究小组不久前发布的一项研究所提出的一些问题，进行了答疑。

Crtc3 was activated in response to catecholamine signals, when it reduced adenyl cyclase activity by upregulating the expression of Rgs2, a GTPase-activating protein that also inhibits adenyl ...

We compared the signatures derived from all candidate resistance genes to a Library of Integrated Network-Based Cellular Signatures (LINCS) signature of adenyl cyclase stimulation and found that ...