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In the present work, we attempted to enhance the efficacy of this strategy for the delivery of adenoviral vectors using virus-microbead conjugates. A particular focus was placed on the enhancement ...
The engineered viruses, called adenoviral vectors, are designed to shuttle a gene from SARS-CoV-2, the novel coronavirus that causes COVID-19, into our bodies where our cells will read it and make ...
Adenoviral vectors will transduce a wide range of target cells resulting in high-level gene expression. They are non-integrating vectors so expression in dividing cells is progressively lost. First ...
Future Oncol. 2009;5(3):339-357. Clinical trials of oncolytic adenoviral gene therapy in ovarian cancer are due to commence shortly. They will proffer valuable data on toxicity and safety and the ...
We conclude that the antibodies induced by adenoviral vector–based Covid-19 vaccination (classic VITT) and the VITT-like antibodies induced by natural adenovirus infection are extremely similar.
HIV-positive Kaposi sarcoma and immune checkpoint blockade. This is an ASCO Meeting Abstract from the 2018 ASCO-SITC Clinical Immuno-Oncology Symposium. This abstract does not include a full text ...
RECIST 1.1 versus immune-related RECIST and immune-related response criteria in assessing response to nivolumab in patients with lung, renal, and head and neck cancers. Measurement of PD-1, TIM-3 and ...
Muir et al. suggested that coronavirus 2019 (Covid-19) vaccines using an adenoviral (Ad) vector platform may be related to the occurrence of thrombotic thrombocytopenia. Recent reports by ...
A single, intranasal dose of fast-acting adenoviral vaccines protects hamsters against highly lethal Nipah virus April 14, 2025 The virus is endemic in Bangladesh and India, where outbreaks have ...
Patients with a corneal ulcer, trauma, allergy to Dacron, or recent medication use were excluded. AdenoPlus is sensitive and specific for detecting adenoviral conjunctivitis. Abbreviations: CC‑IFA, ...
Among the different types of viral vectors, adenoviral (Ad) vectors have been used for a long time and have now received renewed attention due to the recent approvals of Ad vector–based COVID-19 ...
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