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近日,中国科学院武汉植物园高磊团队在 International Journal of Biological Macromolecules 期刊在线发表了题为“ Identification of long-chain acyl-CoA synthetase gene family reveals that SlLACS1 is essential for cuticular wax ...
And, not surprisingly, it did: fatty acyl-CoA synthetase. This is an enzyme that plays a key role in fat metabolism, creating an intermediary that allows cells to add more carbons onto growing ...
As companies continually search for next-generation obesity prospects, one of the leaders in the disease space, Novo Nordisk A/S, has obtained an exclusive license to a preclinical-stage, ...
Comparatively, in the genus Acremonium, isopenicillin N is converted into penicillin N via a two-enzyme system that involves both acyl-CoA-synthetase and acyl-CoA-racemase. The genes for beta ...
LX9851, discovered and developed by Lexicon, is a potent and selective oral small molecule inhibitor of Acyl-CoA Synthetase 5 (ACSL5) . ACSL5 plays a key role in the metabolic pathway which ...
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is a genetic condition that prevents the body from breaking down fat stores for energy. It can be fatal without early diagnosis and treatment.
Very long-chain acyl-CoA dehydrogenase deficiency (VLCAD), a rare inherited genetic condition, is caused by mutations in the ACADVL gene. It is associated with a disorder in fatty acid metabolism ...
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