The three-carbon pyruvic acid molecules are converted to a two-carbon molecule attached to Coenzyme A, called acetyl CoA, via the process of pyruvate oxidation. It is the product, acetyl CoA ...

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists. The findings ...

A study from Van Andel Institute reveals that immune cells use two pathways, ACLY and ACSS2, to produce acetyl-CoA, an essential metabolite for fighting infection and cancer. These findings highlight ...

Also called the Krebs cycle or the tricarboxylic acid cycle, the process begins with sugar-derived pyruvate, which enzymatically generates acetyl-coenzyme A (CoA) to start the cycle. Acetate released ...