By mimicking RHIMs, Nsp13 triggers an aggressive cell death in human proteins such as ZBP1 and RIPK3 to amplify ... to the respiratory complications and disease progression seen in Covid-19 ...

Nsp13 was found to work in synergy with host RHIM proteins called ZBP1 and RIPK3 to promote cell death activation, which might possibly be contributing to the respiratory damage and disease ...