Lurie Children’s Hospital of Chicago, Illinois. The tool’s name is a mouthful: patient-derived orthotopic xenograft (PDOX) mouse models of childhood brain cancers. Broken down, it means that ...

Several parents had concerns around animal models although some preferred mouse models over zebrafish as they felt that mice were more human-like and thus more valid. Participants expressed that they ...

The effects of OR3 on xenograft mouse models were evaluated by tumor volume measurement, hematological analysis, and histopathological observation. The characterization of OR3 was also performed ...

A recent study explored the therapeutic potential of hu128.1, a humanized antibody targeting transferrin receptor 1 (TfR1), in treating erythroleukemia using xenograft mouse models. The results ...

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host-protective vaccine or therapeutic approaches that elicit potent NK cell-mediated recall responses in vivo To enable our studies, we routinely utilize mouse models, xenograft models, and clinical ...