Wnt信号通路（Wnt signaling pathway）作为神经系统发育的关键调控者，其基因变异与老年人轻度认知障碍（MCI）的关联机制尚不明确。来自山东青岛的研究团队对17个村庄459名老年人展开横断面研究，检测9个Wnt通路基因的46个单核苷酸多态性（SNP），采用蒙特利尔 ...

These signalling systems operate beyond cell and tissue boundaries, but function as morphogens that are secreted from one cell or tissue type to activate surface receptors, signal transduction ...

Of particular significance was the finding that T3 rapidly repressed the expression of a host of key regulators of the tumor-promoting Wnt signaling pathway and the transcriptional activity of the ...

研究结论和讨论部分指出，TMEM176B 在卵巢癌中发挥着重要的抑癌作用，它通过调节 Wnt/β-catenin 信号通路的激活来抑制 EMT，进而阻碍卵巢癌的进展。这一发现不仅揭示了 TMEM176B ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

NOTCH signaling influences these traits through interactions with other pathways like TGF-β, WNT, and hypoxia signaling. The ...

The Wnt signaling pathway is a conserved network that regulates cell proliferation, differentiation, and migration. It ...

The anti-melanogenesis effect of ligustroside derived from Ligustrum japonicum and its underlying mechanisms are explored.

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...

Surrozen will focus its Wnt biology expertise and Wnt signal modulation antibody technologies on its ophthalmology programs including development of new treatment options for retinopathies. Other ...