Future research will therefore demonstrate how important the Wnt–β-catenin signalling pathway is for the self-renewal of cancer stem cells. The past two decades have seen a number of cases in ...

结果发现 SLC2A1 在 CRC 中上调，与转移和不良预后相关，Yes 相关蛋白 1（YAP1）可激活 SLC2A1 转录，YAP1-SLC2A1 轴激活 Wnt/β-catenin 信号通路。这为 CRC 治疗提供新靶点。 在癌症的世界里，结直肠癌（Colorectal Cancer，CRC）是一个极为棘手的难题，它在全球范围内广泛肆虐 ...

It turns out that they use Wnt–β-catenin signalling to determine where the head and the tail should form. Figure 1: Wnt–β-catenin signalling regulates head and tail formation during ...

这些结果表明 CGREF1 在肝癌细胞中可能作为癌基因发挥作用。 CGREF1 激活肝癌细胞中的 Wnt/β-Catenin 信号通路：利用基因集富集分析（GSEA）发现 CGREF1 与 Wnt/β-Catenin 信号通路密切相关。进一步研究发现，过表达 CGREF1 可通过降低 p-β-Catenin 水平、增加 β-Catenin 水平来 ...

Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...

The Wnt signaling pathway is a conserved network that regulates cell proliferation, differentiation, and migration. It ...

The research reveals that MAFB and CCAAT/enhancer-binding protein alpha (CEBPA) regulate urothelial cell growth via the Wnt/β-catenin signaling pathway, offering new insights into the genetic ...

Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with more than one million new diagnoses annually.

Allarity Therapeutics, Inc. (“Allarity” or the “Company”) (NASDAQ: ALLR), a Phase 2 clinical-stage pharmaceutical company ...

By understanding how SOX9 governs Wnt/β-catenin signaling and EMT, we can identify potential new therapeutic strategies to treat this condition." The implications of these findings extend beyond ...