Several recently reported structures reveal the details of ribosome architecture and provide new insights into the mechanism of protein synthesis. Although high quality diffracting crystals of the ...

"Ribosomes are very large macromolecular machines that very rapidly and precisely decode mRNA into protein. For a long time, they've been viewed as kind of 'dumb code-reading machines' that don't ...

A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

We showed that non-AUG translation is strikingly resistant to multiple protein synthesis inhibitors, including cycloheximide. We find that these inhibitors slow elongating ribosomes, thereby inducing ...