Ribonucleic Acid (RNA) polymerase is an intermediary enzyme responsible for processing gene sequences into RNA-based genetic material that can be utilized in protein synthesis. In this article, we ...

There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...

Ribonucleic Acid (RNA) polymerase is an intermediary enzyme responsible for processing gene sequences into RNA-based genetic material that can be utilized in protein synthesis. In this article, we ...

The nomenclature of different promoter-associated RNA polymerase II (Pol II) species is explicitly defined in an effort to provide consistency in future literature. The known mechanistic features ...

Figure 1: Antibodies to β-actin inhibit RNA polymerase II transcription in vivo. Figure 2: Antibodies to β-actin inhibit RNA polymerase II transcription in vitro. Figure 3: β-actin is ...

RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...

This enables the RNA polymerase (RNAP) and the ribosome to coordinate their functions and work together efficiently directly.

In the early 1990s, direct injection of nucleic acids (RNA or DNA) into the muscles of mice led to in vivo expression of proteins encoded by the injected nucleic acid. 1 This finding, together ...

They can afford the longer genomes due to the presence of a unique protein, in addition to the RNA polymerase, that performs the proofreading function. RNA polymerases are also capable of ...

structure of the RNA-dependent RNA polymerase (RdRp), which is a key part of the virus’s replication machinery that makes copies of its RNA genome (Science 2020 10.1126/science.abb7498).