Next-generation DNA sequencing has started a revolution in genomics and created the opportunity for large-scale sequencing projects, such as the recently announced 1,000 Genomes Project—an ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Most of your DNA will look just like that of any other person. But tiny differences in the spelling or sequence of those letters in thousands of genes across your genome explain, in part ...

The gold standard technology that scientists use to detect DNA methylation is bisulfite genomic sequencing. It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at ...

Next-generation sequencing (NGS) has made analyzing DNA faster and cheaper, with effects felt in the lab, clinic, and beyond. A set of newly-launched technologies are offering a twist on the ...

DNA has two strands. Each strand is a sequence of four chemical bases: adenine (A), cytosine (C), guanine (G), and thymine (T). The strands are anti-parallel and complementary. ‘Anti-parallel ...

Advances in clinical genomics have been enabled by short-read sequencing (SRS) technologies, where the DNA is broken into pieces up to 300 base pairs long. While these technologies have many ...