在这项最新研究中，研究团队发现了一个具有与端粒结合蛋白 TRF1/TRF2 类似的 Myb/SANT-like DNA 结合结构域的新蛋白——MSANTD4（Myb/SANT-like DNA-binding domain-containing ...

In the present study, we established the human 293-derived cell lines, which expressed exogenously truncated WRN protein, lacking the N-terminal exonuclease domain but having normal helicase activity, ...

Currently, we are elucidating roles for the DNA repair protein WRN in preserving telomeres. Defects in the WRN protein causes the premature aging disorder Werner syndrome and accelerated loss of ...