Since vitamin D is known to repress renin gene transcription ... Streptozotocin was used to induce diabetes in 8-week-old mice. At 2 weeks after streptozotocin injection, mice were randomly ...

The fact that they did not observe this effect in mice with deficiencies in other immunity-related genes that underwent the same treatments validated Gc as the protein linking vitamin D metabolism ...

Mice with low vitamin D had exaggerated craving for opioids and felt the drugs’ effects more strongly—results supported in part by human medical records—suggesting that supplements should be explored ...