The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the ...

In addition, we use other complementary methods such as X-ray crystallography and biochemistry to help connect the path from structure to function. Our recent research focuses on human pathogenic ...

The Ebola and Marburg viruses use polymerase complexes to replicate and transcribe their genome. Here, the authors present cryo-EM structures of the polymerase complexes of both viruses and ...

A major challenge lies in the virus's structure and regulatory mechanisms, which have remained largely unclear. In particular, scientists have long struggled to fully understand its nucleocapsid ...

His research involves studying the structure of viruses and how they interface with the cells of their hosts’ bodies ... “Even if we have an unknown virus of the same group, we can predict where the ...

Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...

These structures have been detected in approximately 7% of gut bacteria and 50% of oral bacteria samples worldwide, ...