本研究旨在探讨Slit2对体外血管内皮细胞增殖和迁移的影响，并揭示可能的潜在信号通路。从Sprague Dawley大鼠身上分离主动脉内皮细胞并进行培养。随后进行细胞增殖试验、细胞迁移试验、免疫细胞化学和小干扰RNA转染。结果表明，外源性Slit2可显著抑制TNF - α诱导的内皮细胞增殖和体外迁移。（本段内容为AI翻译，原始内容请见官网） ...

These findings suggest that, although VEGF signaling may be a rate-limiting step in a wide variety of circumstances, local regulatory pathways modulate endothelial-cell growth and function in a ...

Two independent studies show that ephrin-B2 controls the internalization and signaling of two types of vascular endothelial growth factor (VEGF) receptors—thereby regulating VEGF-induced ...

Our study suggests that activation of VEGF-B signaling in white adipose tissue and the kidney together contributes to higher release of fatty acids into the blood, leading to increased lipid ...