BNT327, a PD L1/VEGF antibody, belongs to a class of next-generation immunotherapies hoping to beat out Keytruda.

Disease progression eventually occurs in many patients that were included in these trials, raising the issue that undiscovered pathways mediate angiogenic escape after VEGF inhibition. Different ...

A research team led by the Guangzhou Institutes of Biomedicine and Health of the Chinese Academy of Sciences has constructed ...

These findings suggest that, although VEGF signaling may be a rate-limiting step in a wide variety of circumstances, local regulatory pathways modulate endothelial-cell growth and function in a ...

the mechanism by which this pathway is upregulated in patients with BAVM is uncertain. The effects of serum starvation and vascular endothelial growth factor (VEGF) stimulation on the Notch signalling ...

The Eylea franchise was in need of a win after an appellate court last week denied the pharma’s bid to block Amgen’s biosimilar from the U.S.

The drug is designed to block the PD1 and VEGF pathways while minimising VEGF-related adverse effects, "specifically due to its intentionally designed interaction with VEGFR2," according to Ottimo.

Tharimmune (THAR) announced preclinical data from its expanded pipeline with HS1940, a dual-target multispecific biologic engineered to bind to ...

Compass Therapeutics, Inc.’s CMPX share price has dipped by 24.55%, which has investors questioning if this is right time to ...

Expert Rev Ophthalmol. 2013;8(6):527-537. In patients that underwent cataract surgery, baseline aqueous levels of IL-6, IP-10, VEGF and macrophage chemotactic protein (MCP)-1 were higher in ...