Impairment of the ubiquitin/proteasome system has been proposed to play a role in neurodegenerative disorders such as Alzheimer and Parkinson diseases. Although recent studies confirmed that some ...

The ubiquitin–proteasome system regulates transcriptional control at many levels, and involves both proteolytic and non-proteolytic activities. Histone ubiquitylation forms part of the 'histone ...

A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São ...

To answer these questions, the group plans to conduct comparative transcriptome and proteomic analyses of the wild and mutant strains cultivated under respiratory conditions. The goal is to establish ...

A study by the Center for Redox Processes in Biomedicine ( Redoxoma ) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil ...

The ubiquitin proteasome system (UPS) regulates the ubiquitination, and thus degradation and turnover, of many proteins vital to cellular regulation and function. The UPS comprises a sequential series ...

The ubiquitin proteasome system (UPS) regulates the ubiquitination, and thus degradation and turnover, of many proteins vital to cellular regulation and function. The UPS comprises a sequential series ...

Proteasome phase separation for destruction. Tokyo Metropolitan Institute of Medical Science. Journal Nature DOI 10.1038/s41586-020-1982-9 ...

A Complex Role in Cellular Process & Growing Tool Set to Elucidate It It is increasingly clear that the ubiquitin-proteasome-system (UPS) is misnamed. Ubiquitylation is not just about targeting ...

Time for the Ubiquitin-Proteasome System #3 These papers look very interesting and show the relevance in Alzheimer disease of an efficient working protein quality control by the ubiquitin-proteasome ...

Proteasome Activator Enhances Survival Of Huntington's Disease Neuronal Model Cells. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2007 / 02 / 070228064850.htm ...

In this new editorial, researchers Xiaoling Li and Ping Mu from the University of Southwestern Medical Center discuss the ubiquitin-proteasome system (UPS), which is usually responsible for ...