Neddylation, the covalent attachment of ubiquitin-like protein Nedd8, of the Cullin-RING E3 ligase family regulates their ubiquitylation activity. However, regulation of HECT ligases by ...

The abundant homohexameric AAA+ ATPase p97/VCP (Cdc48 in yeast) participates in a wide range of cellular processes, including cell cycle regulation, endoplasmic reticulum (ER)-associated ...

论文标题为“NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly”。 图片来自Kheewoong Baek/MPI of Biochemistry。 诸如免疫应答或细胞增殖之类的 ...

论文标题为“NEDD8 nucleates a multivalent cullin–RING–UBE2D ubiquitin ligation assembly”。 图片来自Kheewoong Baek/MPI of Biochemistry。 诸如免疫应答或细胞增殖之类的 ...

2007年自然出版集团宣布《Nature》出版集团的新出版物、名为Nature China的网站（www.naturechina.com.cn）正式启动。这一网站致力于聚焦中国大陆地区和香港的优秀科学成果，每周都会针对最新发表的论文，在此网站撰写摘要和评述。 生物通报道：2007年自然出版集团 ...

cerevisiae and human. In addition, we also characterzed a ’ulp’ type protease that is able to deconjugate Nedd8 rather than SUMO and a viral protease that removes lysine 48-linked ubiquitin chains two ...

Discovery of a NEDD8 modification system regulating the cell cycle: During in vitro translation analysis of full-length cDNA clones, a ubiquitin-like protein, NEDD8, was found to covalently modify ...

Neddylation is a post-translational modification that conjugates the NEDD8 protein to protein substrates, such as the cullins, which once neddylated join complex to form cullin-RING ubiquitin E3 ...

Please use one of the following formats to cite this article in your essay, paper or report: APA Smith, Yolanda. (2023, July 20). Ubiquitin-Like Modifiers. News-Medical. Retrieved on June 13, 2025 ...

Please use one of the following formats to cite this article in your essay, paper or report: APA Smith, Yolanda. (2018, August 23). Ubiquitin and Diseases. News-Medical. Retrieved on June 14, 2025 ...