In individuals with a compromised type 1 interferon system, severe viral infections can occur because the body cannot mount a full defense. Recent research has shown that about 5 to 15% of people ...

Autoantibodies are involved in autoimmune diseases like rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and lupus. Immunoglobulin M (IgM) is also one of the first antibodies recruited ...

Adults and older children undergoing reinfection probably constitute an important source of infection for susceptible infants. For this reason it would be desirable to develop immunoprophylactic ...

The identification of diabetes-relevant islet autoantibodies is essential for predicting and preventing type 1 diabetes (T1D). The aim of the current study was to evaluate a newly developed ...

MHH team aims to intervene in the autoimmune process and stop the destruction of insulin-producing beta cells in the pancreas ...

The current findings are consistent with our previous finding [5] that an ECL-IAA assay is able to detect disease-relevant, high-affinity autoantibodies ... or undetermined-type diabetes will ...