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14 天
IRF4 在 Th17 和 iTreg 细胞中调控程序的综合特征分析
辅助性 T 细胞 17(Th17)细胞在自身免疫性疾病的发生和发展中起着重要作用,其发育高度依赖 IRF4 的表达。调节性 T 细胞(Treg)细胞则有助于维持外周免疫耐受,防止自身攻击性免疫反应。虽然 Treg 细胞的产生不直接依赖 IRF4,但 IRF4 对其在特定环境和组织中的 ...
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