Therefore, exosomes represent a novel source of tumor-rejection antigens for T-cell cross priming, relevant for immunointerventions.

the antigens that mediate tumor rejection should be identified. Although Vile and coworkers have convincingly shown that CD8 + T cells play a crucial role in tumor growth control, no information ...

All of the cancer vaccines discussed here are therapeutic vaccines. They are designed to stimulate the patients' immune system to recognize and reject their own cancer after it has been diagnosed.

These newly recognized cancer-specific proteins, or antigens, could speed the development of potent immunotherapies that recognize and attack hard-to-treat tumors. The study, which was supported ...

Using T cell receptor sequencing on both functionally expanded T cells and neoantigen-loaded tetramer-sorted T cells, we identified tumor antigen-specific T cell receptors,” write the investigators.

Although many antigens are expressed on both normal and cancerous ... the subsequent immune response that triggers organ rejection can also eliminate the cancer, even when it has metastasized beyond ...

Mayo Clinic researchers have discovered a new immunotherapy target, a cryptic antigen, that may be key in helping the immune ...

I was a postdoc at Sloan Kettering in 1985, and I had just received the results of the N-terminal sequence of gp96, a tumor-rejection antigen, which I had purified from a mouse sarcoma, and earlier ...

This means that tumor suppression was directly related to the presence of antigen, not the nutritional value of the food or any specific antigen. The three diets also affected immune cells ...