A recent study has uncovered key insights into the differing tumour rejection behaviours of chimeric antigen receptor T cells ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

"In this study, we asked whether the RNLS protein could potentially be a tumor antigen by examining chemical ... of ...

avoid rejection by the host immune system and provide durable responses. “Our engineered cells express T cell receptors and/or CARs that have been optimized to target multiple cancer antigens ...

B cells contribute to the rejection of skin allografts by presenting donor antigens to T cells, via opsonizing donor cells (through binding of alloantibodies) and via direct complement-dependent ...

A new advance may make it possible to use off-the-shelf CAR T cells provided by healthy donors. The new approach studied in mice equipped CAR T cells with the viral protein Nef.