Vaccines have had a major impact on the control of infectious disease, most recently by helping to combat the COVID-19 ...

A study in Chemistry A European Journal reveals that reduced MUC1 antigen density on gold nanoparticles still elicits potent ...

These therapies involve programming the T-cell receptor (TCR) of T cells to recognize a specific peptide, or antigen, found on tumor cells. There are many efforts underway to identify the most ...

Breakthrough nanovaccine uses tumor cell membranes and immune-boosting polymers to enhance personalized cancer immunotherapy, ...

In the field of cancer immunotherapy, unconventional T cells (UCTs) and Chimeric Antigen Receptor (CAR) T cells have emerged as promising areas of research ...

IL-12 is produced in antigen-presenting cells and ... suppress or enhance tumor growth depending on the tumor microenvironment. Finally, the peptide increases IL-12p70 production from T cells ...

These therapies involve programming the T-cell receptor (TCR) of T cells to recognize a specific peptide, or antigen, found on tumor cells. There are many efforts underway to identify the most ...

(6) Soluble TCR and TCR mimics are small proteins that bind peptides and engage with the CD3ε subunit of the endogenous TCR to create a synthetic immunological synapse. (7) A T cell antigen coupler ...

Different immunogenic antigens characterized in solid ... White blood cell; WT1: Wilms tumor gene 1. Interesting targets for peptide vaccination have been defined including Wilms tumor gene ...

The poster, “Characterization of Antigen-Agnostic Tumor-Selective Delivery and Immunomodulatory Activities of Auristatin and Maytansinoid alphalex™ Peptide-Drug Conjugates,” highlighted ...