Primary metabolic pathways, which are usually active and synthesize the small molecules used by most organisms most of the time, make single products. The tryptophan pathway makes tryptophan ...

Tryptophan 2,3-dioxygenase (TDO), as a key rate-limiting enzyme, is widely involved in tryptophan metabolism and the regulation of various physiological and pathological processes. TDO activity can be ...

These changes mostly affected the phenylalanine, tyrosine, and tryptophan pathway and the phenylalanine metabolism pathway. Negative relations to the total abnormal involuntary movement scale score ...

The research highlights the complex role of tryptophan metabolism in cancer. While tryptophan is known to be metabolized into several important compounds, including the neurotransmitter serotonin ...

Solving the atomic structure of seven intermediates provided a detailed view of the enzyme’s chemistry. HAO belongs to the KP metabolic pathway, which breaks down tryptophan for use in the ...

These changes mostly affected the phenylalanine, tyrosine, and tryptophan pathway and the phenylalanine metabolism pathway. Negative relations to the total abnormal involuntary movement scale ...