Mediators of anaphylactic reactions:- Aside from mast cell tryptase, which other chemical inflammatory mediators offer potential as indicators of anaphylaxis? Why this is important:- Although mast ...

High amounts of tryptase, a chemical associated with mast cell activation, were detected in blood testing. SM was verified by a bone marrow biopsy. But unlike most cases, this patient's condition ...

The concern is primarily due to robust tryptase reduction being linked to hematological adverse events (AEs), including a decrease in hemoglobin levels. This toxicity issue is expected to limit ...