Mediator—a general transcription factor—may acquire gene-specific functions that are triggered by TF binding. One focus of the lab is to study how TFs regulate Mediator structure and function. To do ...

The answer lies in transcription factors. Experiments have shown that ... believed to be part of the activation process. Chromatin structure allows activators to associate with one another ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...

Chromatin structure is highly complex and impressively ... nucleosomes essentially act as a physical barrier to transcription factors that need to bind to certain regions of DNA.

The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

SnapShot: Mediator Complex Structure. Cell 2022 ... Architecture of the human and yeast general transcription and DNA repair factor TFIIH. Mol Cell 2015, 59: 794 – 806. Allen, BL; Taatjes, DJ. The ...

Thus, transcription-factor proteins can bind to several different ... initiation sites the group found was in root nodules, a structure on legumes' roots that harbors interaction between the ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by ...