The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...

These TF-specific structural states may direct gene-specific regulatory events; in other words, Mediator—a general transcription factor—may acquire gene-specific functions that are triggered by TF ...

Three of the conserved non-ligand residues in the Zn module are basic residues that project from the helices and extended structure (Lys 16, His 18 and Lys 19). Side chains of these residues may ...

SnapShot: Mediator Complex Structure. Cell 2022, 185: 3458 ... Architecture of the human and yeast general transcription and DNA repair factor TFIIH. Mol Cell 2015, 59: 794 – 806. Allen, BL; Taatjes, ...

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by which periodic chemical signal frequencies in cells regulate gene ...

Thus, transcription-factor proteins can bind to several different ... initiation sites the group found was in root nodules, a structure on legumes' roots that harbors interaction between the ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by ...