This Tortoiseshell Cat has a PhD in teaching life lessons, and her little human sister takes it all in stride with the best of spirits. Check out these cute siblings and their laugh-out-loud antics in ...

Dilute tortoiseshell coloring occurs due to a recessive gene that causes a softening of the coat colors. So, instead of dark black and bright orange, these cats will have a soft grey (softened ...

The mom behind @russellranchaussies' TikTok account knew this day was coming, but I can only imagine the smile on her face as she watches her Australian Shepherds and tortoiseshell cat swarm the ...

Spots can be visible in everything. While some might consider it to be bad, for others it is a sign of beauty. Here are some ...

Jean is a tortoiseshell cat, while Jorts is large, sweet and orange. While Jean is overall fairly intelligent, Jorts is not. This follows the stereotypes many cat lovers joke about: tortoiseshell ...

Samantha Rose Baldwin, an actress who appeared in the Gossip Girl reboot, detailed the “terrifying” experience of running through the Palisades Fire to save her 10-year old tortoiseshell cat ...

A prime example of X inactivation is in the coat-color patterning of tortoiseshell or calico cats (Figure 1). In cats, the fur pigmentation gene is X-linked, and depending on which copy of the X ...

This is why most calico and tortoiseshell cats, which have a mix of black and brown fur, are female. In somatic cells, only one of the two X chromosomes is active, and as a result, the black and ...