Diagnosis Tophaceous gout associated with urate nephropathy in a patient intolerant to allopurinol. Management Acute polyarthritis was successfully managed by intravenous bolus methylprednisolone ...

Treatment of gout takes a two-pronged approach, comprising treatment of acute flare-ups of gouty arthritis, and urate-lowering therapy in some patients. Several medications can be used for the ...

Tophi are a collection of uric acid crystals that accumulate underneath the skin. Gout occurs from high levels of uric acid ...

The medical community has long been looking for this new mechanism in gout to address the shortcomings with conventional MOAs, especially where it comes to treating refractory and tophaceous patients.

Arthrosi Therapeutics, Inc., a late-stage biotechnology company developing a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate (sUA) levels, ...

In the U.S., an estimated 13 million individuals are diagnosed with gout, ~2 million of which have tophaceous gout. Gout is a form of inflammatory arthritis that can significantly diminish ...