it is conceivable that TRAIL is differentially expressed in Th1 and Th2 cells. Since Th1 cells are sensitive to TRAIL- and CD95L-induced apoptosis, these cells could be the targets of TRAIL- or ...

为了揭开这些谜题，来自加利福尼亚大学欧文分校的研究人员在《Cell Stem Cell ... 诱导强烈的 Th1 细胞分化，并且在培养期剩余时间内保持较高水平，还能引发更高频率的记忆 CD8 细胞；而非活抗原（IIVs 和亚单位疫苗）刺激的 T 细胞则主要呈现 Th2 表型。

Effects of mangiferin on cell proliferation 研究发现芒果苷对静息态淋巴细胞无毒性，但能浓度依赖性地抑制PHA诱导的增殖。100 μM芒果苷的抑制效果与地塞米松相当，证实其免疫抑制潜力。 该研究首次证实芒果苷能特异性调节人类淋巴细胞功能，其双重抑制Th1/Th2但不 ...

Like Th1 and Th2 cells, Th17 cells produce a group of distinctive cytokines — interleukin-17 (also called interleukin-17A), interleukin-17F, interleukin-22, and interleukin-21 — all of which ...

These cells express a balanced Th2/Th1 effector phenotype -- a T-cell profile that is thought to protect against transplant rejection and improve the outcome of patients by reducing graft versus ...

It has been challenging to create T cells that are both potent and durable. In a new study, researchers report the potent anti-tumor properties of hybrid Th1/Th17 cells that combine the cancer ...

these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pathogens, or TH2 cells, which fight against extracellular pathogens like bacteria and parasites.

On antigen presentation, naive T cells are subjected to either interleukin-12 and interleukin-18 or interleukin-4, which polarizes them to Th1 or Th2 helper cells, respectively. Th1 cells produce ...

The result was a hybrid Th1/17 T cell that has the best anti-cancer characteristics of both parent cells. "We've known about how T cells can fight tumors for more than three decades. However ...