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it is conceivable that TRAIL is differentially expressed in Th1 and Th2 cells. Since Th1 cells are sensitive to TRAIL- and CD95L-induced apoptosis, these cells could be the targets of TRAIL- or ...
Effects of mangiferin on cell proliferation 研究发现芒果苷对静息态淋巴细胞无毒性,但能浓度依赖性地抑制PHA诱导的增殖。100 μM芒果苷的抑制效果与地塞米松相当,证实其免疫抑制潜力。 该研究首次证实芒果苷能特异性调节人类淋巴细胞功能,其双重抑制Th1/Th2但不 ...
Like Th1 and Th2 cells, Th17 cells produce a group of distinctive cytokines — interleukin-17 (also called interleukin-17A), interleukin-17F, interleukin-22, and interleukin-21 — all of which ...
these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pathogens, or TH2 cells, which fight against extracellular pathogens like bacteria and parasites.
These cells express a balanced Th2/Th1 effector phenotype -- a T-cell profile that is thought to protect against transplant rejection and improve the outcome of patients by reducing graft versus ...
It has been challenging to create T cells that are both potent and durable. In a new study, researchers report the potent anti-tumor properties of hybrid Th1/Th17 cells that combine the cancer ...
The result was a hybrid Th1/17 T cell that has the best anti-cancer characteristics of both parent cells. "We've known about how T cells can fight tumors for more than three decades. However ...