Continually proliferating cells maintain adequate telomeres through the action of the reverse transcriptase telomerase. Telomeres are important to human health because dysregulation of either telomere ...

These mouse models have provided insights into the function of telomeres and telomerase in the development of neoplastic cells, most notably that impaired telomere function can, in certain genetic ...

5 This checkpoint is important to prevent cells from replicating damaged DNA. Due to this phenomenon, scientists describe telomere length as a biological clock that indicates the lifespan of a cell ...

Telomeres are protective caps at the ends of chromosomes. By adopting stress-reducing habits, you can help preserve them, potentially slowing down aging and improving your health.

It wasn’t completely surprising that there was no change in telomere length. The surprise was how much telomerase was induced. Q: Why was it surprising to see telomerase induction without telomere ...

Telomeres, which cap the ends of chromosomes, play a critical role in this cell-renewal process—with a direct bearing on ...

The three were honored for “for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.” According to the Royal Swedish Academy, this year’s Nobel Prize in Physiology or ...

As presented by Calvin Harley, [12] of Geron Corp. in Menlo Park, California, GRN163, a specific oligonucleotide telomerase inhibitor, is being developed as an anticancer agent. GRN163 is an ...

Located at the ends of eukaryotic chromosomes and synthesized by the enzyme telomerase, telomeres maintain the length of chromosomes. The majority of human cancer cells express high levels of ...

Geron Corporation (Nasdaq: GERN), a commercial-stage biopharmaceutical company aiming to change lives by changing the course of blood cancer, today an ...