Telomerase is a ribonucleoprotein enzyme responsible for maintaining telomere length. 6 This enzyme comprises a telomerase RNA component (TERC) that identifies the telomeric sequence and acts as a ...

After years of hard work, scientists have succeeded in creating genetically-engineered mice that could help accelerate ...

thus validating human telomerase reverse transcriptase as an important target for the development of anti-neoplastic therapies. To determine whether disruption of hTERT catalytic function would ...

Globally, scientists are working to unlock the secrets of extending human lifespan at the cellular level, where aging occurs ...

Researchers have developed HuT mice, a genetically engineered model with human-like telomeres, enabling scientists to study ...

Led by WSU College of Pharmacy and Pharmaceutical Sciences Professor Jiyue Zhu, the research team has developed mice that have human-like short telomeres, enabling the study of cellular aging as it ...

then testing these activities in a reconstituted telomerase assay and validating our knowledge directly in the organism. The telomere provides a protective cap for the linear chomosome ends. In S.

Washington State University scientists have created genetically-engineered mice that could help accelerate anti-aging research.

Cech on the 2009 Nobel Prize in Medicine HHMI investigator Thomas R. Cech, who studies the structure and function of telomerase, discusses the seminal discoveries honored by this year’s prize. Cech ...