T hiazolidinediones (TZDs) are a class of drug that can be used to treat type 2 diabetes by reversing insulin resistance, one of the main hallmarks of the disease. While TZDs were extremely ...

Purpose: A review of the significant findings related to the use of the thiazolidinediones (TZDs) in the treatment of patients with type 2 diabetes mellitus and heart failure was conducted.

The FDA took many TZDs off the market and drugs like Metformin replaced medicines to treat diabetes, but Olefsky and his team didn’t forget about the older drugs. “If you go back to when they ...

Thiazolidinediones (TZDs) are the major drug class used to improve insulin sensitivity in the treatment of type 2 diabetes. However, TZDs have several adverse effects, including weight gain and ...