这项研究发现了TSPO对于小胶质细胞吞噬功能的重要性，阐明其促进小胶质细胞的吞噬依赖于促进线粒体的有氧呼吸。同时还发现了HK移位至线粒体会 ...

为探究肺部炎症中转运蛋白 18kDa（TSPO）的表达水平，研究人员开展了合成新型光学探针的研究。合成的 FITC-MBP 能特异性识别 TSPO，在肺部炎症模型小鼠体内可聚集于肺部，或可用于可视化过表达的 TSPO。 转运蛋白 18kDa（TSPO）已成为探测和监测中枢神经系统（CNS ...

而有研究发现，AD患者的小胶质细胞出现了代谢紊乱[1]。 线粒体转位蛋白（TSPO）是一种可以被正电子断层扫描观察到的炎症标志物，它在AD患者小 ...

糖尿病牙周炎（DP）发病机制不明。研究人员探究转位蛋白（TSPO）在 DP 进展中的作用。发现 DP 患者牙龈线粒体损伤、TSPO 表达增加；TSPO 配体拮抗剂可缓解 DP 大鼠炎症破坏。为 DP 治疗提供新靶点和理论依据。 在健康与疾病的 “战场” 上，牙周炎和糖尿病这 ...

线粒体转运蛋白（TSPO）位于线粒体外膜，参与广泛的线粒体功能，包括氧化应激调节，铁稳态和胆固醇转运。既往研究发现 TSPO 在很多种类肿瘤中 ...

The translocator protein (18 kDa) (TSPO) is a five transmembrane domain protein that is localized primarily in the outer mitochondrial membrane and is expressed predominantly in steroid ...

Specifically, this refers to a molecule called TSPO, which can be detected in the brain by means of positron emission tomography (PET). "We typically associate dementia with elderly people.

The investigators sought to determine whether levels of TSPO VT, which are quantifiable with PET, are elevated in the dorsal putamen, ventral striatum, prefrontal cortex, anterior cingulate cortex ...

A new positron emission tomography (PET) imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein (TSPO) expression in the synovium (joint lining ...

The repair protein, known as 18 kDa translocator protein (TSPO), is known to be present in the brain at high levels in the immediate aftermath of brain injury as part of the inflammatory response and ...