A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the ...

Initially, tRNA was considered merely a transporter of amino acids. This view changed with the discovery of suppressor tRNA. In 1965, Engelhardt et al. experimentally demonstrated that suppressor ...

Unraveling the role of tRNA modifying enzyme in brain function A step towards understanding 'RNA modification diseases' Date: September 27, 2024 Source: Kumamoto University Summary: A ...

Kumamoto [Japan] September 30 (ANI): A pioneering study undertaken by a Kumamoto University research team shed light on the crucial role of TRMT10A, a tRNA methylation enzyme, in sustaining brain ...

Using cryo-EM, researchers at Goethe University (Frankfurt, Germany) shed light on eukaryotic pre-transfer RNA (pre-tRNA) splicing, a key stage in protein production, and rationalize mutations ...

“As a leader in the field of tRNA biology, we look forward to highlighting some of the recent findings from our platform at AARS 2023,” said Leslie A. Nangle, Ph.D., Vice President, Research ...

Structural biology: Molecular scissors caught in the act Structure of an enzyme crucial for tRNA maturation sheds light on cause of neurodegenerative disorders Date: July 13, 2023 Source: Goethe ...

Werner, I’m immediately called upon to dust off my Biology 101 notes to grasp the significance and scope of their transfer RNA (tRNA) therapeutic platform. “Humans only need 47 different tRNAs ...

LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease. The study found age-dependent ...