5-Prime | T-Cell Subsets: On the Immunity Warpath How do T cells recognize their targets? The acquired immune system consists of two major cell types, T and B cells, which recognize specific antigens.

T cells are the immune system’s frontline fighters. When they detect danger, they rapidly multiply and transform into ...

A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

A subset of CD8+ T cells is increased in the blood and inflamed tissues of patients with a variety of autoimmune diseases and in COVID-19 patients with autoimmune-related complications.

RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis patients.

Findings indicate that frequent COVID-19 booster shots do not weaken T-cell responses, alleviating concerns for vulnerable ...

"Our results showed that a subset of T cells, labeled as CD8-fit T cells, are capable of high motility and serial killing, found uniquely in patients with clinical response," reports first author ...

They also identified a T cell subset that can be targeted to treat COPD exacerbations. In a study publishing February 22, 2023 in Immunity, first author Chaoqun Wang, PhD, a UCSF postdoctoral fellow ...