Whereas prior acute GVHD impaired Treg reconstitution, Treg subsets (absolute numbers and frequencies relative to CD4 + T-cell subsets) at 3, 6 and 12 months after HSCT were not associated with ...

Explore a high-throughput picodroplet-based method for CAR-T cell functional validation that enables rapid, single-cell ...

The mammalian immune system is an evolutionary wonder. It's capable of recognizing and destroying cancer cells, and it can ...

Our immune systems develop to recognize what is foreign within our bodies. As immune cells are generated in the bone marrow ...

Certain subsets of immune NK cells were altered in the blood of people with ALS, and could serve as therapeutic targets, a ...

and the differentiation of T cell subsets. The research team investigated the regulatory mechanisms that guide the optimal differentiation of T cells into specific lineages while inhibiting others.

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

Early clinical results suggest the firm's antibodies targeting the Vβ T-cell receptor could induce strong and durable responses in cancer patients.

FDA grants fast track designation to azer-cel, an allogeneic CAR T-cell therapy, for relapsed or refractory diffuse large ...

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...