A new study from Auburn University provides new insights into neuronal connections, offering hope for the treatment of ...

First discovered as proteins found on synaptic vesicles and at the presynaptic plasma membrane, SNAREs are members of a family of highly conserved proteins that reside on vesicles (v-SNAREs ...

Jennifer Morgan, senior scientist at the Marine Biological Laboratory, Woods Hole, studies how the synapse malfunctions in devastating diseases such as Parkinson’s and Lewy body dementia. Now, her lab ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

We also found that the organization of the presynaptic milieu, including both synaptic vesicle pools and active zone scaffolding complexes, is fluid in nature, and dynamic liquid condensates are ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent ... the presynaptic neuron and restored inside a vesicle ready to be used again.