In summary, we demonstrate that accessory subunits are integrally associated in modules, defined by the core structural and functional subunits of human complex I, assembly of which require the ...

在细胞内膜泡离子稳态研究中，为探究内体 Cl-/H + 交换的调控机制，研究人员开展了关于内体 ClC-3、ClC-4 和 ClC-5 与 TMEM9 及 TMEM9B 关系的研究。结果发现 TMEM9 和 TMEM9B 是内体 CLC 的必需 β - 亚基，可调节其功能。该研究揭示了内体离子运输的调控机制，具有重要 ...

Although it is apparent that NF-κB subunits have important roles in tumorigenesis and the response to cancer therapy, their individual contributions have not been clearly defined. The NF-κB ...

In a landmark discovery, researchers have unveiled the highly dynamic and adaptable architecture of the mammalian pyruvate ...

Neurobiologists have found new evidence that specific calcium channel subunits play a crucial role in the development of excitatory and inhibitory synapses. The ability of the human brain to ...

Three-dimensional images of human small ribosomal subunits offer the most detailed explanation for how the cell's protein-making machines are assembled. All cells need ribosomes to make the ...

These structures are comprised of two major ribonucleoprotein subunits. The smaller subunit mediates the correct interactions between three consecutive, in-frame base pairs, called codons and the ...

A scientist says he has shown that it’s possible to produce a large amount of virus-like particles using a fully scalable ...

Co-mutational status and PD-L1 expression in KRAS mutant non-small cell lung cancer (NSCLC): Role in treatment selection and association with clinical outcomes.

NMDA receptors are composed of four distinct subunits: two glycine-binding GluN1 subunits and two glutamate-binding GluN2 subunits. These subunits are assembled in a heterotetrameric way to form a ...

Ludwig-Maximilians-Universitaet (LMU) in Munich chemists led by Oliver Trapp show that a simple reaction pathway could have given rise to DNA subunits on the early Earth. How were the building ...