引言蛋白质（proteins）在细胞（cells）内拥有各自特定的“地址”（subcellular ...

麻省理工学院和哈佛大学的团队提出了一种结合了蛋白质序列和细胞图像来进行未知蛋白质亚细胞定位的预测框架 PUPS。该框架创新地结合了蛋白质语言模型和图像修复模型来预测蛋白质定位，使其兼并推向未知蛋白预测的泛化能力和捕获细胞可变性的细胞类型特定预测。

The subcellular signaling landscape of receptors. G protein-coupled receptors (GPCRs) form the largest receptor family in humans. GPCRs mediate the effects of diverse natural liga ...

Knowledge of the subcellular localization of proteins is important because it can (i) provide useful insights about their functions, (ii) indicate how and in what kind of cellular environments ...

Mapping a human cell gives researchers a view of subcellular architecture and sheds light on how cancer develops.

The technique builds upon and uses superresolution microscopy, which provides clearer images of particles at the subcellular level. "So we measure the relative distance between organelles like ...

Teams of scientists are currently using the groundbreaking subcellular spatial analysis technology to help resolve daunting challenges in COVID-19 pathology, neurology, and developmental biology ...

These battery-free, subcellular-sized devices, made of a soft polymer, are designed to gently wrap around different parts of neurons, such as axons and dendrites, without damaging the cells ...

Biologic diversity of breast cancers in women with African ancestry. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This abstract does not include a full text component.

Subcellular chatter regulates longevity Lysosome to mitochondria communication Date: May 19, 2020 Source: Max-Planck-Gesellschaft Summary: As people get older, they often feel less energetic ...

"We need to be able to see all these different functional components—cells, their morphology and their connectivity, subcellular architectures, and their individual synaptic connections ...