A new peer-reviewed Perspective (review) article shows that many widely-used prescription medications unintentionally disrupt sterol biosynthesis, a critical process for brain development. This ...

Caption. Commonly used prescription medications have a post-lanosterol biosynthesis inhibiting effect. Pathogenic variants in the DHCR7 gene result in SLOS with a hallmark sterol inhibition signature.

Željka Korade et al, Sterol biosynthesis disruption by common prescription medications: critical implications for neural development and brain health, Brain Medicine (2025). DOI: 10.61373/bm025p.0011 ...

What we've discovered is that many prescription medications, while designed for entirely different purposes, can inadvertently interfere with the brain's ability to produce and process sterols ...