Small stereochemical changes can bring big distinctions to molecules like drugs, fragrances, and propellants. Switching the stereochemistry of a single substituent can change a rose-scented ...

This article was originally published with the title “ The Stereochemical Theory of Odor ” in Scientific American Magazine Vol. 210 No. 2 (February 1964), p. 42 doi:10.1038 ...

The paper describes a breakthrough method to produce antisense oligonucleotide (ASO) therapeutics with high stereochemical purity as well as rational drug design to control pharmacologic ...

These compounds are essential in the pharmaceutical industry but have been challenging to synthesize with the required stereochemical accuracy. The innovative reagent t-BuSF uses strain-release ...