Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and increasing mutation risks. This phenomenon provides new insights into cancer ...
The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...
Because B-cell lymphoma develops in a type of white blood cell, the team examined their precursors, called hematopoietic stem cells, in the mice. Genetically disrupting inflammasome activity in ...
While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
Techniques that cause multipotent adult mesenchymal stem cells (MSCs) to differentiate into ... by graft of engineered constructs derived from cell-seeded scaffolds; this latter approach could ...
Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy for patients with acute myeloid leukemia (AML) who have ...