Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and increasing mutation risks. This phenomenon provides new insights into cancer ...
“This type of synthetic organizer cell platform provides a new way to interface with stem cells and to program what they develop into,” said Wendell Lim, PhD, the study’s other corresponding ...
“One of the reasons why we have this kind of cellular Swiss bank account [is to protect] the cellular integrity,” said Britta Will, a stem cell biologist at the Albert Einstein College of Medicine.
Boston – Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a standard therapy ...
Because B-cell lymphoma develops in a type of white blood cell, the team examined their precursors, called hematopoietic stem cells, in the mice. Genetically disrupting inflammasome activity in ...
The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...
While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...