Human aging significantly contributes to cognitive decline and increased susceptibility to late-life neurodegenerative diseases (e.g.Alzheimer’ s disease, ...

The local stem cell environment (niche) is vital for stem cell maintenance and function in many tissues, and tenascin C in particular has been shown to play an important role within stem cell niches ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

A single molecular switch is essential for blood stem cells to enter an activated, regenerative state in which they produce new blood cells, according to a preclinical study led by Weill Cornell ...

Schematic Overview of the Development of a Bespoke Islet-specific Microenvironment Using Bioprinting Technology to Enhance ...

FLI-1's activity, in contrast, restores stem cells' connections and co-adaptability with their microenvironmental endothelial cell niche, also known as the vascular niche. FLI-1 pushes them into an ...

An international group of researchers has identified an important mechanism that enables stem cells to evade immune rejection ...

Diabetes is a metabolic disorder caused by dysfunction in the pancreas, the organ responsible for regulating blood sugar levels. Within the pancreas, islet cells secrete insulin to lower blood sugar.

A research team has successfully developed an innovative platform for diabetes treatment using bioink derived from pancreatic ...