However, the inhibition of the mevalonate pathway decreases the formation of coenzyme Q10 (CoQ10) within the body. It has been a long-standing theory that statin-associated muscle pain (myalgia ...

this effect is likely related to the intrinsic potency of the drug used to block HMG-CoA activity and the mevalonate metabolic pathway. Nevertheless, these effects of statins do not seem to be ...

The MVK gene carries instructions to make a protein called mevalonate kinase, which helps your body make cholesterol. You need cholesterol to make steroid hormones, which help your body grow ...