In larger, late stage tumours, mTORC1 suppression by hypoxia may be an adaptive response in the face of energy limitations, thus favouring hypoxic cell survival.

COPD can lead to hypoxia, which is when cells or tissues in your body don’t get as much oxygen as they need. Learn more about its symptoms, causes, and treatments.

PURPOSERecurrence occurs in 20%-30% of early-stage non–small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT). ... Hypoxic Gene Expression Signature as a Predictor of ...

Hypoxic Gene Expression Signature as a Predictor of Recurrence and Mortality in Early-Stage Non–Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy Nicholas J. Eustace , Nikhil T.