This protein is involved in various physiological ... In the work reported here, we demonstrated that STAG1 was strongly induced by p53-121F, and that enforced expression of STAG1 using a ...

STAG2或其同源物STAG1与由SMC1A、SMC3和RAD21组成的三元环状结构相互作用，形成粘附素复合体的核心。STAG2和STAG1有很高的序列相似性，可以部分补偿彼此 ...

Zhang and colleagues have now shown that ARID1A is essential for telomere cohesion as it controls expression of STAG1, a component of the cohesin protein complex. In fact, ablation of ARID1A ...

What is particularly remarkable about this discovery is that these disturbances cannot be compensated for by the STAG1 protein, highlighting the role of STAG2 in AML. In a further step ...

"Actually, cohesin is a protein complex made of multiple subunits," Losada explains. "Cells have two versions of this complex; one of them carries the STAG1 subunit, and the other, the STAG2 subunit.

Zhang and colleagues have now shown that ARID1A is essential for telomere cohesion as it controls expression of STAG1, a component of the cohesin protein complex. In fact, ablation of ARID1A ...

Cohesin is a ring-shaped protein that surrounds and moves around ... In vertebrate cells, there are two versions of cohesin, known as STAG1 cohesin and STAG2 cohesin, although it is not known ...