编者按：皮肤鳞癌是全球第二常见的皮肤癌类型，是一类免疫治疗较为敏感的肿瘤。在本次ASCO大会上，有多项2期研究提示，新辅助免疫治疗皮肤鳞癌的pCR率可达50%以上；而既往报道的辅助免疫治疗大多宣告失败。在皮肤鳞癌患者中，新辅助免疫治疗能否取代手术、放 ...

After Bicara reported a 12-month OS of 61% for its HPV-negative population last week, biotech Merus shared that its ...

【导读】二硫键修饰对于维持蛋白质结构和活性至关重要，但其在调节肿瘤干细胞特性及化疗耐药性方面的作用仍鲜为人知。5月28日，中山大学/郑大一附院研究人员合作共同在期刊《Advanced ...

In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the ...

A phase II clinical trial led by the Alliance for Clinical Trials in Oncology has met its primary endpoint, demonstrating ...

综上，LSM12 在肺鳞状细胞癌（LUSC）细胞中表达上调，促进了 LUSC 细胞在体外的增殖、迁移和侵袭，并在体内增强了肿瘤的形成和转移。本研究结果为 LUSC 的发展以及 LSM12 在 LUSC 细胞中的作用研究提供了基础。

Researchers are also investigating the PD-1 immune checkpoint inhibitor as treatment before surgical and radiation treatment.

Adjuvant Opdivo, cisplatin and radiotherapy improved DFS vs other treatment among those with locally advanced squamous cell ...

CHICAGO – The postoperative addition of nivolumab (Opdivo) to chemoradiotherapy (CRT) extended disease-free survival (DFS) in ...