Movement is a complex process governed by a network of neuronal circuits spread across multiple regions of the nervous system ...

In vertebrates, motor neurons (also called motoneurons) are efferent neurons that originate in the spinal cord and synapse with muscle fibers to facilitate muscle contraction and with muscle ...

Hyperrelexic, overactive or spastic bladder or bowels occur with spinal cord injury at or above T12. The primary characteristic of this type of injury is increased organ spasms. The UMN bladder may ...

The spinal cord bladder and bowel reflex arc is damaged in patients with injuries to the cauda equina, lumbar and sacral segments below the conus medullaris. Patients do not typically transition to an ...

In the spinal cord, tau pathology leads to a dramatic loss of motor neurons ... develops by 5 to 6 months of age (Allen et al., 2002). In addition to motor neuron loss, these mice also lose ...

Spinal cord surgery to restore motor trajectories ... response from their motor neurons (the F-response). The motor neuron response from peripheral nerve stimulation on the unaffected side ...

A motor neuron disease MND patient has been named the Australian of the Year for 2025 for his work to find a cure for the neurodegenerative conditio ...